Congratulations to Jisoo Shin, Subhajit Pal, Miles Conrad and the rest of the team for their recent paper published in Journal of Vascular Intervention and Radiology (JVIR)!
Hydrodissection is a procedure performed during cryoablation of tumor tissue, in which liquids such as saline or 5% dextrose in water is injected at the periphery of the tumor in an effort to create a buffer zone between the treatment target and sensitive tissue such as the bowel or body wall. Low viscosity liquids often flow away from the site, reducing the insulating effect. The paper describes an injectable shear-thinning hydrogel for tissue separation during percutaneous cryoablation, providing a potentially more effective hydrodissectant compared to saline.
Citation:
Jisoo Shin, Bradley H. King, Subhajit Pal, Bita Rezaian, Shervin Zoghi, Eric M. Mastria, Miles B. Conrad, Phillip B. Messersmith, “Injectable, Dual-Cross-Linked, Dynamic Hydrogel for Tissue Separation and Thermal Shielding during Percutaneous Cryoablation”, Journal of Vascular and Interventional Radiology, Volume 37, Issue 6, 2026, 108686.
Link to the paper